As admittedly posted with LNR, The Time Traveller's Wife is fab... But a long term favourite, (and given that you're relatively geeky you've almost definitely read it already but hey) try The Sparrow (jesuits in spaaaaaaace) by Mary Doria Russell - one of the best novels in the world ever.
The Sparrow is terribly wonderful, it's scifi but essentially is about the nature of faith and humanity, I cried A LOT. Do grab it if you get a chance, or you could just borrow it from me, I also have the follow-up Children of God.
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